僅用于工業(yè)應(yīng)用或科學(xué)研究,不可用于人類或動物的臨床診斷或治療,非藥用.Sorafenib tosylate is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. 甲苯磺酸索拉非尼是Raf-1和B-Raf的多激酶抑制劑,在無細胞測定中IC50分別為6nM和22nM。甲磺酸索拉非尼抑制VEGFR-2、VEGFR-3、PDGFR-β、Flt-3和c-KIT,IC50分別為90 nM、20 nM、57 nM、59 nM和68 nM