僅用于工業(yè)應(yīng)用或科學(xué)研究,不可用于人類或動物的臨床診斷或治療,非藥用.Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.Abiraterone 是一種有效的不可逆的 CYP17A1 抑制劑,具有抗雄激素活性,抑制細(xì)胞色素 p450 酶 CYP17 的 17α-羥化酶和 17,20-裂合酶活性,IC50 值 分別為 2.5 nM 和 15 nM